Research Articles
Automated Systems for C. elegans Growth and Motility Quantification: A Guide to High-Throughput, AI-Driven Analysis
This article provides researchers, scientists, and drug development professionals with a comprehensive overview of the latest automated platforms for quantifying Caenorhabditis elegans growth and motility.
Industrial Scale High-Throughput Screening for Anti-Wolbachia Drug Discovery: Methods, Challenges, and Breakthroughs
This comprehensive review explores the application of industrial-scale high-throughput screening (HTS) in the discovery of anti-Wolbachia compounds for treating filarial nematode infections.
AI-Powered Microscopy: Revolutionizing Helminth Egg Detection and Classification for Biomedical Research
This article comprehensively examines the transformative role of artificial intelligence (AI) in the image-based classification of helminth eggs, a critical diagnostic task in parasitology.
High-Throughput Screening for Anthelmintic Discovery: Modern Strategies to Combat Gastrointestinal Nematodes
Gastrointestinal nematode (GIN) infections represent a significant global health and economic burden, with current anthelmintic treatments threatened by rising drug resistance.
SYBR Green I Flow Cytometry in Malaria Research: A Comprehensive Guide for High-Throughput Growth Inhibition Assays
This article provides a comprehensive overview of the application of SYBR Green I-based flow cytometry for assessing malaria parasite growth and inhibition.
WMicrotracker ONE: A High-Throughput Phenotypic Platform for Anthelmintic Screening and Resistance Detection in Haemonchus contortus
The WMicrotracker ONE instrument, which uses infrared light interference to quantitatively measure nematode motility, has emerged as a powerful tool for anthelmintic discovery and resistance monitoring.
FA280 Fully Automatic Digital Feces Analyzer: Protocol, Performance, and Application in Biomedical Research
This article provides a comprehensive analysis of the Orienter Model FA280, a fully automatic digital feces analyzer, detailing its operational protocol, diagnostic performance, and application in parasitology and clinical research.
INVAPP and Paragon: Revolutionizing High-Throughput Chemical Screening for Parasite and Vector Control
This article details the INVertebrate Automated Phenotyping Platform (INVAPP) combined with the Paragon algorithm, a robust system transforming high-throughput screening for novel anthelmintics and larvicides.
High-Throughput Screening for Plasmodium falciparum Blood Stages: From Foundational Assays to Clinical Candidate Discovery
High-throughput screening (HTS) is a pivotal strategy in antimalarial drug discovery, enabling the rapid evaluation of compound libraries against Plasmodium falciparum blood stages to address rising drug resistance.
Automated Digital Feces Analyzers in Parasitology: A Technological Revolution for Research and Diagnostics
This article provides a comprehensive analysis of automated digital feces analyzers and their transformative role in intestinal parasite detection.